New progress in the research of basic and applied diamond film materials

Abstract Electrochemical biosensor is a technology that converts chemical signals generated by reaction with specific biometric units into electrical signals. It has the advantages of high sensitivity, fast response speed, low cost, small portability, etc., in clinical medicine, environmental detection and Inspection and quarantine and other aspects have important work...

Electrochemical biosensor is a technology that converts chemical signals generated by reaction with specific biometric units into electrical signals. It has the advantages of high sensitivity, fast response speed, low cost, small portability, etc. in clinical medicine, environmental testing and inspection. Quarantine and other aspects play an important role. The highly catalytically active metal oxide recognition unit is one of the important development directions of electrochemical biosensing technology. However, the metal oxide identification unit has low conductivity, which seriously hinders the electron transfer process during the reaction, and the sensing performance is not good. Therefore, from the perspective of designing high-efficiency electrochemical biosensor electrode structure, it is the focus and difficulty of research in this field to construct a highly conductive nano-film structure conversion unit to load high catalytic activity recognition unit.
Institute of Metals and Materials Research, Department of Thin Film Materials and Interfaces, Institute of Materials Science and Research, Institute of Materials Science and Technology, Institute of Materials Science, Institute of Materials Science and Technology, Ph.D., Ph.D., Ph.D., Ph.D., Ph.D., Ph.D., CVD, PVD and electrochemical oxidation technology. CuO's three-dimensional network electrochemical sensing electrode is used for the detection of glucose molecules. The electrochemical sensing electrode exhibits a wide linear detection range (0.5×106 -4×103 M), high sensitivity (1650 A cm-2 mM-1), low detection limit, and good selectivity and excellent reproduction. Sexual and long-term stability, further research found that the electrode showed a good recovery rate (94.21-104.18%) in the actual analysis of human serum, with high biomolecular recognition ability. Analysis shows that the excellent electrochemical sensing performance is mainly due to the diamond/carbon nanowall film electrode with excellent physicochemical properties. On the one hand, carbon nanowalls are composed of dozens of graphene sheets grown almost perpendicular to the substrate, which not only have excellent electrical conductivity and large specific surface area, but also have abundant electrochemically active graphite edges and are easy to pass. The quality of the open pore structure, not easy to agglomerate, structural stability and so on. On the other hand, high Young's modulus diamond penetrates the entire thin film electrode in the form of nanosheets, further improving the mechanical structural stability of the electrode during application. This unique three-dimensional network structure accelerates the mass transfer of glucose molecules and timely transports electrons generated by the catalytic reaction back to the electrochemical loop, thereby demonstrating excellent electroanalytical performance and long-term stability. In addition, the three-dimensional network electrochemical sensing electrode is also suitable for loading other biometric units, and exhibits great potential in the field of high performance electrochemical biosensors. The carbon nanostructure will also have research value in the fields of electrochemical energy storage and conversion, electrocatalysis and the like. Relevant research results were invited to be published in Small (in press, https://doi.org/10.1002/smll.201901527).

The above basic research work has been funded by the National Natural Science Foundation of China, the Liaoning Provincial Science and Technology Fund, and the Shenyang Municipal Science and Technology Achievement Transformation Project.

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Fig.1 Schematic diagram of three-dimensional network diamond/carbon nanowall-loaded CuO nanoparticle electrochemical sensing electrode structure and biosensing detection
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Figure 2 Three-dimensional network diamond/carbon nanowall loaded CuO electrochemical sensor electrode sensitivity, anti-interference, selectivity and long-term stability test

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