Improving the overall immune function of the herd and restoring vitality are fundamental to controlling pig disease. The causes of low immunity in pigs are increased density of culture, environmental stress, feed mycotoxin, infection with Mycoplasma hyopneum, infection with blue ear virus, etc., which reduces the overall immunity of the herd and becomes a very vulnerable group. High-throughput screening system and features High-throughput screening, also known as large-scale cluster screening, is a highly automated and highly sensitive new technology for screening and discovering new drugs developed at the end of the 20th century. Its screening capacity is more than 1 million samples per year or The compounds were screened for biological activity, including five subsystems: a high-volume sample library, an automated operating system, a high-sensitivity detection system, a data processing system, and a specific drug screening system. It plays an important role in the screening process of active ingredients of traditional Chinese medicine. Classic Cellular Immunomodulator Levamisole has both the regulation of cellular immunity and humoral immunity, with cellular immune regulation as the main factor, and the immune function is restored to normal levels. The amount of feed additive is 20ppm, which can be continuously added for 2 weeks to 3 weeks. Humoral immune regulator The feed of Astragalus polysaccharide as an immunomodulator is 120 ppm, which can be used for 3 weeks to 8 weeks. It should be noted that as an immunopotentiator, it should be applied in small amounts. The most promising immune anti-inflammatory Chinese herbal preparations Glycyrrhizin has an immuno-anti-inflammatory effect in the screening of Chinese herbal immunomodulators. Glycyrrhizic acid is one of the most important active ingredients in licorice. It has anti-inflammatory, anti-viral and liver-protecting functions, detoxification and immune enhancement. Because glycyrrhizin has glucocorticoid-like pharmacological effects without serious adverse reactions, it is widely used in the treatment of various acute and chronic hepatitis, bronchitis and AIDS. It also has anti-cancer anti-cancer, interferon inducer and cellular immune regulation. Agent and other functions. As the research progresses, other roles of glycyrrhizic acid are being gradually developed. Glycyrrhizin anti-inflammatory effect: The synthesis and release of PGS can be inhibited by the inhibition of phospholipase required for AA hydrolysis. The intraperitoneal injection of glycyrrhizic acid monoamine salt significantly inhibited the chemical auricle redness and peritoneal capillary permeability, and significantly reduced the red, swollen and hot symptoms in acute inflammatory reactions. At the same time, it also has a significant inhibitory effect on rat cotton granuloma, and the anti-inflammatory effect is close to that of dexamethasone. Antiviral action of glycyrrhizic acid: inhibition of viral proliferation and inactivation of virus, antiviral effect is one of the main pharmacological effects of glycyrrhizic acid. In recent years, research and application of glycyrrhizic acid and glycyrrhizin (GL) on hepatitis virus, HIV and other viruses have achieved good results. Glycyrrhizin has excellent properties such as high sweetness, low calorie, foaming and hemolysis, safe and non-toxic, and strong health care. Anticancer effect of glycyrrhizic acid: In addition to its functions of preventing and treating viral liver and inducing interferon, glycyrrhizic acid has anti-cancer and anti-cancer effects. In the experiment of using glycyrrhizic acid to control aflatoxin B and di- and nitrosamine-induced precancerous lesions in rats, it was confirmed that glycyrrhizic acid significantly inhibited the occurrence of precancerous lesions and DNA damage during the pathological process. The repair has obvious protective effect, which makes the DNA repair function close to normal level, thus reducing the carcinogenicity of DNA. Immunomodulatory effects of glycyrrhizic acid: Glycyrrhizin has non-specific immunomodulatory effects, which mainly enhance cellular immunity, enhance phagocytosis, eliminate inhibitory activity, and selectively enhance the proliferative capacity and activity of helper T lymphocytes. . Synergistic effect of interleukins enhances NK cell activity and proliferation. NK cells are an important class of immunoregulatory cells and are the most ideal effector cells in immune surveillance cells. The unique glucocorticoid-like action of glycyrrhizic acid determines its clinical importance and broad application prospects. Glucocorticoids such as dexamethasone are anti-inflammatory, anti-toxin, anti-shock, and anti-immune. The uniqueness of glycyrrhizic acid has anti-inflammatory, anti-toxin, anti-shock, and immune regulation effects. Glycyrrhizic acid is used as an immunomodulator, and the amount of the additive in the feed is 60 ppm. Single Basin Faucet,Bathroom Basin Faucets,Single Hole Basin Tap,Single Handle Basin Faucet AIHUI Sanitary Ware , https://www.aihuisanitary.com
Application of Chinese herbal medicine immunomodulator in livestock and poultry feed